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Risk Assessment of Nanomaterials Toxicity by Andrea Hartwig, Christoph van Thriel is a nonfiction available to read on EtoBox.

What is Risk Assessment of Nanomaterials Toxicity about?

Regarding the increasing use of nanomaterials in almost every area of our daily life, toxicological risk assessment is one of the major requirements for their safe handling. Especially at workplaces, inhalation is the major route of exposure and potential toxicity, and effects on the lung need to be considered. Furthermore, neurotoxicity associated with exposure to nanomaterials is a growing field of scientific investigation. However, not every single nanomaterial can be assessed in long-term animal inhalation studies, due to limited resources as well as political and societal efforts to reduce animal experiments according to the 3R principles. Thus, during the last few years, significant efforts have been dedicated to grouping nanomaterials, mainly based on advanced in vitro models. These new approach methodologies (NAMs) include detailed characterization of the respective materials in physiologically relevant media, but also more realistic exposure systems, such as co-cultures, also at the air-liquid interface, combined with comprehensive cellular investigations that provide quite detailed toxicological profiles. Thus, nanoparticles show differences in toxicity depending on their

Who reads Risk Assessment of Nanomaterials Toxicity?

Author

Andrea Hartwig, Christoph van Thriel

Publisher

MDPI AG

Published

2023

Language

EN

ISBN

9783036578132

Category

nonfiction

Subjects

Engineering, Stem