Skip to content

Opening book details…

Can I read Regulation of Gene Expression in the Tumor Environment: Regulation of melanoma progression by the microenvironment: the roles of PAR-1 and PAFR (The Tumor ... on EtoBox?

Regulation of Gene Expression in the Tumor Environment: Regulation of melanoma progression by the microenvironment: the roles of PAR-1 and PAFR (The Tumor ... by Menashe Bar-Eli is a nonfiction available to read on EtoBox.

What is Regulation of Gene Expression in the Tumor Environment: Regulation of melanoma progression by the microenvironment: the roles of PAR-1 and PAFR (The Tumor ... about?

<p><P>It is now becoming very clear that the development and progression of tumor towards the malignant (metastatic) phenotype depends tightly on the interaction between the tumor cells and the tumor microenvironment. Tumor cells respond to stimuli generated within the tumor microenvironment for their growth advantage while the tumor cell themselves reshape and remodel the architecture and function of their extracellular matrices. The term tumor microenvironment is a wide umbrella consisting of stromal cells such as fibroblasts and endothelial cells and infiltration immune cells including T and B cells, macrophages, and other inflammatory cells (PMNs). These different components of the tumor microenvironment could have stimulatory and inhibitory effects on tumor progression by regulating the gene expression repertoire within the tumor cells on one hand and the stroma cells on the other. In this volume we have seven contributors who will discuss several different aspects on the cross talk within the tumor microenvironment components leading to the acquisition of the metastatic phenotype. It is our hope that these state-of-the-art studies will shed further light on our understanding

Who reads Regulation of Gene Expression in the Tumor Environment: Regulation of melanoma progression by the microenvironment: the roles of PAR-1 and PAFR (The Tumor ...?

It is typically read by self-directed learners exploring a subject in depth.

Common subject areas: history, science, philosophy, social sciences.

Author
Menashe Bar-Eli
Publisher
Springer Science+Business Media B.V
Published
2008
Language
EN
ISBN
9781402083419
Category
nonfiction
Subjects
Science, Medical, Biology

Other editions & translations

More by Menashe Bar-Eli

Browse all works by Menashe Bar-Eli

Similar books