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What is Aspartame about?

The study by Wu et al. reveals that aspartame consumption exacerbates atherosclerosis through an insulin-dependent mechanism, increasing insulin levels and promoting inflammation via the CX3CL1-CX3CR1 signaling pathway. Experiments demonstrated that aspartame feeding in mice led to significant atherosclerotic plaque formation, which was mitigated by the deletion of the Cx3cr1 gene. These findings suggest potential therapeutic targets for treating atherosclerosis-related cardiovascular diseases.

Author

Phát Phạm

Language

EN