Can I read Projections to the Subcortical Forebrain from Anatomically Defined Regions of the Medial Geniculate Body in the Rat on EtoBox?

Projections to the Subcortical Forebrain from Anatomically Defined Regions of the Medial Geniculate Body in the Rat by Joseph E. LeDoux; David A. Ruggiero; Donald. J. Reis is a Neuroscience article available to read on EtoBox.

What is Projections to the Subcortical Forebrain from Anatomically Defined Regions of the Medial Geniculate Body in the Rat about?

Although the auditory cortex is believed t o be the principal efferent target of the medial geniculate body (MG), our recent behavioral studies indicate that in rats the conditioned coupling of emotional responses to an acoustic stimulus is mediated by subcortical projections of the MG. In the present study we have therefore used WGA-HRP as an anterograde and retrograde axonal marker to (1) define the full range of subcortical efferent projections of the MG; (2) identify the cells of origin within the MG of each projection; and (3) determine whether the subregions of the MG that project to subcortical areas receive inputs from acoustic relay nuclei of the midbrain, particularly the inferior colliculus. The rat MG was first parcelled into three major cytoarchitectural areas: the ventral, medial, and dorsal divisions. The suprageniculate nucleus, located within the body of the MG just dorsal to the medial division, was also identified. Efferent projections of the MG were determined by combined anterograde and retrograde tracing methods. Injections of WGA-HRP in the MG produced anterograde transport to cortex and several subcortical areas, including the posterior caudate-putamen and a

Who reads Projections to the Subcortical Forebrain from Anatomically Defined Regions of the Medial Geniculate Body in the Rat?

Author

Joseph E. LeDoux; David A. Ruggiero; Donald. J. Reis

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 0021-9967)

Published

1985

Language

EN

Field

Neuroscience (Life Sciences)