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Body Fatness, Related Biomarkers and Cancer Risk: an Epidemiological Perspective by Katharina Nimptsch; Tobias Pischon is a Medicine article available to read on EtoBox.
What is Body Fatness, Related Biomarkers and Cancer Risk: an Epidemiological Perspective about?
## Abstract Higher body fatness is not only associated with a higher risk of hypertension, type 2 diabetes, and coronary heart disease but also with certain types of cancer. The scope of this review is to summarize the epidemiological evidence for an association between body fatness and specific types of cancer and to outline the mediating role of obesity-related biomarkers in this context. Epidemiological studies have gathered convincing evidence that greater body fatness is associated with a higher risk of colorectal cancer, postmenopausal breast cancer, endometrial cancer, esophageal adenocarcinoma, renal cell carcinoma, and pancreatic cancer. Further, evidence for an association between higher body fatness and higher risk of ovarian cancer, advanced prostate cancer, and hepatocellular carcinoma is growing. Abdominal obesity is an independent risk factor for colorectal cancer beyond general obesity, whereas an independent role is less clear for other obesity-related cancer types. Epidemiological biomarker studies have shown that the positive association between body fatness and risk of cancer may be partly explained by hyperinsulinemia and altered concentrations in adipokines an
Who reads Body Fatness, Related Biomarkers and Cancer Risk: an Epidemiological Perspective?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Katharina Nimptsch; Tobias Pischon
- Publisher
- Walter de Gruyter GmbH
- Published
- 2015
- Language
- EN
- Field
- Medicine (Health Sciences)