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Elucidating the Potential Side Effects of Current Anti-Seizure Drugs for Epilepsy by Enes Akyüz; Betül Köklü; Cansu Ozenen; Alina Arulsamy; Mohd. Farooq Shaikh is a Neuroscience article available to read on EtoBox.

What is Elucidating the Potential Side Effects of Current Anti-Seizure Drugs for Epilepsy about?

Over the decades, various interventions have been developed and utilized to treat epilepsy. However, the majority of epileptic patients are often first prescribed anti-epileptic drugs (AED), now known as anti-seizure drugs (ASD), as the first line of defense to suppress their seizures and regain their quality of life. ASDs exert their anti-convulsant effects through various mechanisms of action, including regulation of ion channels, blocking glutamate-mediated stimulating neurotransmitter interaction, and enhancing the inhibitory GABA transmission. About one-third of epileptic patients are often resistant to anti-convulsant drugs, while others develop numerous side effects, which may lead to treatment discontinuation and further deterioration of quality of life. Common side effects of ASDs include headache, nausea and dizziness. However, more adverse effects, such as auditory and visual problems, skin problems, liver dysfunction, pancreatitis and kidney disorders may also be witnessed. Some ASDs may even result in life-threatening conditions as well as serious abnormalities, especially in patients with comorbidities and in pregnant women. Nevertheless, some clinicians had observed

Who reads Elucidating the Potential Side Effects of Current Anti-Seizure Drugs for Epilepsy?

Author

Enes Akyüz; Betül Köklü; Cansu Ozenen; Alina Arulsamy; Mohd. Farooq Shaikh

Publisher

Bentham Science Publishers Ltd.

Published

2021

Language

EN

Field

Neuroscience (Life Sciences)