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Can I read Repeat Computed Tomography Simulation to Assess Lumpectomy Cavity Volume During Whole-Breast Irradiation on EtoBox?
Repeat Computed Tomography Simulation to Assess Lumpectomy Cavity Volume During Whole-Breast Irradiation by Todd W. Flannery; Elizabeth M. Nichols; Sally B. Cheston; Kimberley J. Marter; Shahid A. Naqvi; Kristen M. Markham; Imran Ali; Majid M. Mohiuddin is a Medicine article available to read on EtoBox.
What is Repeat Computed Tomography Simulation to Assess Lumpectomy Cavity Volume During Whole-Breast Irradiation about?
Purpose: To determine whether the lumpectomy cavity (LPC) decreases in volume during whole-breast radiotherapy (RT) and what factors influence the decrease. Patients and Methods: Forty-three women with 44 breast lesions were prospectively enrolled. Eligible patients underwent lumpectomy followed by a CT simulation (CT1) within 60 days of surgery. Patients were treated to the entire breast to a dose of 45-50.4 Gy. After 21-23 treatments, a second planning CT simulation (CT2) was done. The LPC was contoured on CT2, and the volumes (LCV) were compared between CT1 and CT2. Results: The median LCV on CT1 and CT2 was 38.2 cm 3 and 21.7 cm 3 , respectively. The median percent change and volume decrease between CT1 and CT2 was À32.0% and 11.2 cm 3 , respectively (n = 44). The LCV decreased in 38 of 44 patients (86%). There was a significant correlation between initial LCV and decrease in volume (p = 0.001) and initial LCV and percent decrease in volume (p < 0.001). There was no correlation between time from surgery to CT1, to start of RT, or to CT2 and change in volume. Conclusions: Patients who undergo lumpectomy almost always have a decrease in their LCV during whole-breast RT. There was
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- Author
- Todd W. Flannery; Elizabeth M. Nichols; Sally B. Cheston; Kimberley J. Marter; Shahid A. Naqvi; Kristen M. Markham; Imran Ali; Majid M. Mohiuddin
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)
- Published
- 2009
- Language
- EN
- Field
- Medicine (Health Sciences)