About this document
Meningioma Genetic Alterations Review by Apriyanto Latief is a document available to read on EtoBox.
This document summarizes genetic and molecular alterations in meningiomas and the signaling pathways involved. It finds that monosomy 22 and mutations in the NF2 tumor suppressor gene are the most common alterations, occurring in around half of meningioma cases. Other less common genetic changes in chromosomes 1, 6, 9, 10, 14, 18 and sex chromosomes are also associated with meningiomas. The NF2 gene codes for the merlin protein, which regulates cell growth and adhesion through several signaling pathways lik
- Author
- Apriyanto Latief
- Language
- EN