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Can I read Time-dependent protective efficacy of Trolox (vitamin E analog) against microcystin-induced toxicity in tilapia (Oreochromis niloticus) on EtoBox?
Time-dependent protective efficacy of Trolox (vitamin E analog) against microcystin-induced toxicity in tilapia (Oreochromis niloticus) by Ana Isabel Prieto; Angeles Jos; Silvia Pichardo; Isabel Moreno; María Álvarez de Sotomayor; Rosario Moyano; Alfonso Blanco; Ana María Cameán is a Environmental Science article available to read on EtoBox.
What is Time-dependent protective efficacy of Trolox (vitamin E analog) against microcystin-induced toxicity in tilapia (Oreochromis niloticus) about?
## Abstract Microcystins (MCs), hepatotoxins from cyanobacteria, induce oxidative stress and pathological changes in fish that can be ameliorated with chemoprotectants such as vitamin E (vit E). This study investigated the time period after MCs exposure in which Trolox, a vitamin E analog, is effective against oxidative and histological damage in different organs of tilapia (__Oreochromis niloticus__). Fish were fed Trolox supplement (700 mg/kg diet) for 7 days, or received only commercial fish food, and then were exposed to a single oral dose of 120 μg/fish microcystin‐LR, and sacrificed in 24, 48, or 72 h. The Trolox protective efficacy was evaluated based on lipid peroxidation (LPO), protein oxidation, enzymatic and non‐enzymatic antioxidants, and a morphologic study. Regarding the oxidative stress biomarkers altered by MCs, the higher protective action of Trolox was observed 24 h post toxin exposure, although it extends also until 48 h in gills (superoxide dismutase (SOD), catalase (CAT)), and liver, where glutathione reductase (GR) backed to control values 48 and 72 h after the toxin application. Glutathione‐S‐ transferase (GST) activity in the liver was ameliorated by the che
Who reads Time-dependent protective efficacy of Trolox (vitamin E analog) against microcystin-induced toxicity in tilapia (Oreochromis niloticus)?
It is typically read by researchers, students, and practitioners in Environmental Science.
- Author
- Ana Isabel Prieto; Angeles Jos; Silvia Pichardo; Isabel Moreno; María Álvarez de Sotomayor; Rosario Moyano; Alfonso Blanco; Ana María Cameán
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1520-4081)
- Published
- 2008
- Language
- EN
- Field
- Environmental Science (Physical Sciences)