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What is Beta-Thalassemia in India & Middle East about?

This document summarizes beta-thalassemia, focusing on regions including the Indian Subcontinent and Middle East. It discusses the molecular basis of beta-thalassemia, resulting from mutations in the HBB gene. Over 535 mutations have been characterized, with about 40 mutations responsible for most cases globally. Clinical severity ranges from beta-thalassemia major to intermedia to minor. Common mutations vary by geographic region. Improved understanding of mutation distributions in at-risk areas may enhanc

Author

lananhslss

Language

EN