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Permanent Sacral Nerve Stimulation for Treatment of Idiopathic Constipation by N. J. Kenefick; R. J. Nicholls; R. G. Cohen; Professor M. A. Kamm is a Medicine article available to read on EtoBox.

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## Abstract ## Background Constipation can usually be managed using conservative therapies. A proportion of patients require more intensive treatment. Surgery provides variable results. This paper describes an alternative approach, in which the neural control of the bowel and pelvic floor is modified, using permanent sacral nerve stimulation. ## Methods Four women (aged 27–36 years), underwent temporary and then permanent stimulation. All had idiopathic constipation, resistant to maximal therapy, with symptoms for 8–32 years. Clinical evaluation, bowel diary, Wexner constipation score, symptom analogue score, quality of life questionnaire and anorectal physiology were completed. ## Results There was a marked improvement in all patients with temporary, and in three with permanent, stimulation. Median follow-up was 8 (range 1–11) months. Bowel frequency increased from 1–6 to 6–28 evacuations per 3 weeks. Improvement occurred, at longest-follow-up, in median (range) evacuation score (4 (0–4) versus 1 (0–4)), time with abdominal pain (98 (95–100) versus 12 (0–100) per cent), time with bloating (100 (95–100) versus 12 (5–100) per cent), Wexner score (21 (20–22) versus 9 (1–20)), analogu

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Author

N. J. Kenefick; R. J. Nicholls; R. G. Cohen; Professor M. A. Kamm

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square; Oxford University Press (OUP) (ISSN 0007-1323)

Published

2002

Language

EN

Field

Medicine (Health Sciences)