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Can the Computed Tomography Texture Analysis of Colorectal Liver Metastases Predict the Response to First-line Cytotoxic Chemotherapy? by Etienne Rabe; Dania Cioni; Laura Baglietto; Marco Fornili; Michela Gabelloni; Emanuele Neri is a Medicine article available to read on EtoBox.
What is Can the Computed Tomography Texture Analysis of Colorectal Liver Metastases Predict the Response to First-line Cytotoxic Chemotherapy? about?
## BACKGROUND Artificial intelligence in radiology has the potential to assist with the diagnosis, prognostication and therapeutic response prediction of various cancers. A few studies have reported that texture analysis can be helpful in predicting the response to chemotherapy for colorectal liver metastases, however, the results have varied. Necrotic metastases were not clearly excluded in these studies and in most studies the full range of texture analysis features were not evaluated. This study was designed to determine if the computed tomography (CT) texture analysis results of non-necrotic colorectal liver metastases differ from previous reports. A larger range of texture features were also evaluated to identify potential new biomarkers. ## AIM To identify potential new imaging biomarkers with CT texture analysis which can predict the response to first-line cytotoxic chemotherapy in non-necrotic colorectal liver metastases (CRLMs). ## METHODS Patients who presented with CRLMs from 2012 to 2020 were retrospectively selected on the institutional radiology information system of our private radiology practice. The inclusion criteria were non-necrotic CRLMs with a minimum size of
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- Author
- Etienne Rabe; Dania Cioni; Laura Baglietto; Marco Fornili; Michela Gabelloni; Emanuele Neri
- Publisher
- Baishideng Publishing Group Inc.
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)