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Can I read Fluctuating Reaction Rate and Non-exponential Blinking Statistics in Single-enzyme Kinetics on EtoBox?
Fluctuating Reaction Rate and Non-exponential Blinking Statistics in Single-enzyme Kinetics by Jau Tang; Yi-Cheun Yeh; Po-Tse Tai is a Physics and Astronomy article available to read on EtoBox.
What is Fluctuating Reaction Rate and Non-exponential Blinking Statistics in Single-enzyme Kinetics about?
Extending the Michaelis-Menten kinetic scheme, we consider a three-state diffusion-controlled reaction model to investigate the effects of fluctuating reaction rate on the blinking statistics of single-enzyme catalytic reactions. As a result of conformational changes, the barrier-height and the reaction rate for the bottleneck enzymatic reaction could fluctuate in time, leading to non-exponential blinking statistics. To illustrate model applications, some reported experimental data for single b-galactosidase molecules were reanalyzed here to extract useful kinetic parameters.
Who reads Fluctuating Reaction Rate and Non-exponential Blinking Statistics in Single-enzyme Kinetics?
It is typically read by researchers, students, and practitioners in Physics and Astronomy.
- Author
- Jau Tang; Yi-Cheun Yeh; Po-Tse Tai
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0009-2614)
- Published
- 2008
- Language
- EN
- Field
- Physics and Astronomy (Physical Sciences)