Opening book details…
Can I read Pharmacogenetics of Asthma on EtoBox?
Pharmacogenetics of Asthma by A. Fenech; I. P. Hall is a Medicine article available to read on EtoBox.
What is Pharmacogenetics of Asthma about?
Recent advances in the extent of knowledge regarding interindividual genetic variation in drug treatment targets and drug metabolizing enzymes has resulted in studies designed to assess the contribution of genetic variability to treatment response in a range of diseases. This review describes the current state of knowledge of genetic variability in key airway targets important in the treatment of asthma. Whilst the genes coding for some key treatment targets contain little polymorphic variation (e.g. the muscarinic M~2~ and M~3~ receptors) other genes whose products are important targets in the treatment of asthma contain extensive genetic variation. The best examples of the latter are the β~2~‐adrenoceptor and the 5‐lipoxygenase genes. Genetic variability in both of these genes may account in part for interindividual variability in treatment response. Finally, a number of key targets within the airways remain to be adequately screened for polymorphic variation.
Who reads Pharmacogenetics of Asthma?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- A. Fenech; I. P. Hall
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley; Research Square (ISSN 0306-5251)
- Published
- 2002
- Language
- EN
- Field
- Medicine (Health Sciences)