Can I read 2,4‐Dihydroxy‐5‐[(5‐mercapto‐1 H ‐1,2,4‐triazole‐3‐yl)diazenyl]benzaldehyde acetato, chloro and nitrato Cu(II) complexes: Synthesis, structural characterization, DNA binding and anticancer and antimicrobial activity on EtoBox?

2,4‐Dihydroxy‐5‐[(5‐mercapto‐1 H ‐1,2,4‐triazole‐3‐yl)diazenyl]benzaldehyde acetato, chloro and nitrato Cu(II) complexes: Synthesis, structural characterization, DNA binding and anticancer and antimicrobial activity by Mohamed Gaber; Shaimaa K. Fathalla; Hoda A. El‐Ghamry is a Chemistry article available to read on EtoBox.

What is 2,4‐Dihydroxy‐5‐[(5‐mercapto‐1 H ‐1,2,4‐triazole‐3‐yl)diazenyl]benzaldehyde acetato, chloro and nitrato Cu(II) complexes: Synthesis, structural characterization, DNA binding and anticancer and antimicrobial activity about?

Acetato, chloro and nitrato Cu(II) complexes of a novel azo compound, namely 2,4‐dihydroxy‐5‐[(5‐mercapto‐1__H__‐1,2,4‐triazole‐3‐yl)diazenyl]benzaldehyde, have been prepared. The stoichiometry, stereochemistry and bonding fashion of these copper chelates were deduced via elemental analyses, spectral methods and conductivity and magnetic measurements. Infrared spectral data confirmed the participation of azo N atom and the deprotonated OH group. UV–visible spectral data and magnetic measurements indicated octahedral stereo‐structure for the acetato and nitrato compounds and square planer for the chloro compound. Thermogravimetric analysis was applied to investigate the thermal degradation of the metal chelates. The thermo‐kinetic parameters were computed. The molecular modeling technique was used to support the predicted geometry of the prepared chelates. The interaction between the Cu(II) complexes and calf thymus DNA was studied using two techniques: absorption and viscosity measurements. The values of binding constant obtained from the absorption spectral method were calculated and found to be 4.23 × 10^4^, 26.93 × 10^4^, 13.01 × 10^4^ and 5.36 × 10^4^ M^−1^ for ligand and aceta

Who reads 2,4‐Dihydroxy‐5‐[(5‐mercapto‐1 H ‐1,2,4‐triazole‐3‐yl)diazenyl]benzaldehyde acetato, chloro and nitrato Cu(II) complexes: Synthesis, structural characterization, DNA binding and anticancer and antimicrobial activity?

Author

Mohamed Gaber; Shaimaa K. Fathalla; Hoda A. El‐Ghamry

Publisher

Wiley

Published

2019

Language

EN

Field

Chemistry (Physical Sciences)