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What is A Pilot Randomized Trial of Pediatric Cystic Fibrosis Pulmonary Exacerbations Treatment Strategies about?
This document summarizes a pilot randomized trial that assessed the feasibility of comparing two treatment strategies for pediatric cystic fibrosis pulmonary exacerbations (PEx): immediate oral antibiotics versus "tailored therapy" with increased airway clearance and optional delayed antibiotics. The study enrolled 121 participants with cystic fibrosis across 10 US sites. It found that conducting such a randomized trial was feasible and that assigning participants to tailored therapy reduced antibiotic expo
- Author
- Iuri Nascimento
- Language
- EN