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This study presents a simple ELISA method for determining the avidity of anti-dsDNA antibodies, which are crucial for the diagnosis and monitoring of systemic lupus erythematosus (SLE). High avidity anti-dsDNA antibodies are more specific for SLE and correlate with renal involvement, while the developed assay can differentiate between high and low avidity antibodies. The method was validated through a study involving 101 SLE patients and showed consistent results over time, highlighting its potential utilit
- Author
- Javi Miquel
- Language
- EN