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Role of second look endoscopy in endoscopic submucosal dissection and peptic ulcer bleeding: Meta-analysis of randomized controlled trials by Gowthami Sai Kogilathota Jagirdhar; Jose Andres Perez; Akshat Banga; Rakhtan K Qasba; Ruman K Qasba; Harsha Pattnaik; Muhammad Hussain; Yatinder Bains; Salim Surani is a Medicine article available to read on EtoBox.

What is Role of second look endoscopy in endoscopic submucosal dissection and peptic ulcer bleeding: Meta-analysis of randomized controlled trials about?

## BACKGROUND Second-look endoscopy (SLE) to prevent recurrent bleeding in patients with peptic ulcer disease (PUD) and those undergoing endoscopic submucosal dissection (ESD) is routinely being performed. Conflicting evidence exists regarding efficacy, risk, benefit, and cost-effectiveness. ## AIM To identify the role and effectiveness of SLE in ESD and PUD, associated rebleeding and PUD-related outcomes like mortality, hospital length of stay, need for endoscopic or surgical intervention and blood transfusions. ## METHODS A systematic review of literature databases PubMed, Cochrane, and Embase was conducted from inception to January 5, 2023. Randomized controlled trials that compared patients with SLE to those who did not have SLE or evaluated the role of prophylactic hemostasis during SLE compared to other conservative interventions were included. The study was conducted per PRISMA guidelines, and the protocol was registered in PROSPERO (ID CRD42023427555:). RevMan was used to perform meta-analysis, and Mantel-Haenszel Odds ratio (OR) were generated using random effect models. ## RESULTS A total of twelve studies with 2687 patients were included in our systematic review and meta

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Author

Gowthami Sai Kogilathota Jagirdhar; Jose Andres Perez; Akshat Banga; Rakhtan K Qasba; Ruman K Qasba; Harsha Pattnaik; Muhammad Hussain; Yatinder Bains; Salim Surani

Publisher

Baishideng Publishing Group Inc

Published

2024

Language

EN

Field

Medicine (Health Sciences)