Opening book details…
Can I read Regulatory factors involved in Th17/Treg cell balance of immune thrombocytopenia on EtoBox?
Regulatory factors involved in Th17/Treg cell balance of immune thrombocytopenia by Masoud Kargar; Mehdi Torabizadeh; Daryush Purrahman; Zeinab Deris Zayeri; Najmaldin Saki is a Medicine article available to read on EtoBox.
What is Regulatory factors involved in Th17/Treg cell balance of immune thrombocytopenia about?
Immune thrombocytopenia is a common heterogeneous autoimmune disease that is characterized by decreasing peripheral blood platelet counts and increasing risk of bleeding. Studies have shown that an imbalance between T helper 17 (Th17) and Regulatory T (Treg) cells differentiated from CD4+ T-cells is a key factor influencing the development and pathogenesis of immune thrombocytopenia. Th17 cells promote the development of chronic inflammatory disorders and induce autoimmune diseases, whereas Treg cells regulate immune homeostasis and prevent autoimmune diseases. Several regulators affecting the production and maintenance of these cells are also essential for proper regulation of Th17/Treg balance; these regulatory factors include cell surface proteins, miRNAs, and cytokine signaling. In this review, we focus on the function and role of balance between Th17 and Treg cells in immune thrombocytopenia, the regulatory factors, and therapeutic goals of this balance in immune thrombocytopenia.
Who reads Regulatory factors involved in Th17/Treg cell balance of immune thrombocytopenia?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Masoud Kargar; Mehdi Torabizadeh; Daryush Purrahman; Zeinab Deris Zayeri; Najmaldin Saki
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)