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Delayed Hypersensitivity Reactions of Cancer Patients to Antigens on Lymphoid Cell Lines by P. H. Levine; J. H. C. Ho; F. Nkrumah; P. Periman; N. Mourali; G. Cannon; M. B. Middleton; I. V. Perkins; R. Herberman is a Medicine article available to read on EtoBox.

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## Abstract Four‐hundred and fifty niné cancer patients were skin tested with extracts from five lymphoid cell lines. More than 50% of patients with lymphoma had positive skin tests with the extracts prepared from the cell line derived from Burkitt's lymphoma (BL) and more than 50% of nasopharyngeal carcinoma (NPC) patients reacted to the NPC‐derived cell line extracts. Although the significant association between patient diagnosis and origin of cell lines suggested that tumor‐associated antigens were responsible for the pattern of delayed hyper‐sensitivity, problems in standardization of antigen potency and non‐specificity need to be resolved before this __in vivo__ assay achieves its full potential.

Who reads Delayed Hypersensitivity Reactions of Cancer Patients to Antigens on Lymphoid Cell Lines?

Author

P. H. Levine; J. H. C. Ho; F. Nkrumah; P. Periman; N. Mourali; G. Cannon; M. B. Middleton; I. V. Perkins; R. Herberman

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square; Test accounts (ISSN 0020-7136)

Published

1978

Language

EN

Field

Medicine (Health Sciences)