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This systematic review evaluates the efficacy and safety of pharmacological and non-pharmacological therapies for Lennox-Gastaut syndrome (LGS) through a network meta-analysis of 12 randomized controlled trials involving 1,445 patients. Clobazam 1 mg/kg/day, anterior corpus callosotomy, and rufinamide were found to be the most effective interventions for reducing drop seizures, while cannabidiol and lamotrigine were associated with higher risks of adverse events. The study emphasizes the need for caution whe

Author

capslock52003

Language

EN