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What is Enhanced CHO Cell Culture Productivity about?

This document describes a new hybrid perfusion fed-batch cell culture process for producing monoclonal antibodies using CHO cells that provides significantly higher productivity than conventional fed-batch cultures. The process involves a short-duration cell-controlled perfusion phase in the production bioreactor to rapidly expand cells to high density. This is immediately followed by a conventional fed-batch culture with concentrated feeds. This hybrid process approximately doubles overall productivity com

Author

DNav14

Language

EN