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Can I read Understanding the Genomic Background of Multifactorial Skin Diseases on the Example of Plaque Psoriasis on EtoBox?
Understanding the Genomic Background of Multifactorial Skin Diseases on the Example of Plaque Psoriasis by Nikoletta Nagy; University of Szeged Department of Dermatology and Allergology Albert Szent-Györgyi Medical Center; Zsuzsanna Bata-Csörgő; Lajos Kemény; Márta Széll is a Medicine article available to read on EtoBox.
What is Understanding the Genomic Background of Multifactorial Skin Diseases on the Example of Plaque Psoriasis about?
Regarding its genetic and genomic background, psoriasis is one of the most widely dicovered skin disease, therefore it represents the best example to profoundly understand the pathogenesis of multifactorial skin diseases. The exploration of the genetic background of the disease began in the 1970s, the classical linkage studies were performed in the 90s, and the genome wide association studies (GWAS) studies were launched in the early 2000s, elucidating about one third of the genetic background of the disease. Over the past decade intensive research on underlying missing heritability of the disease has revealed epigenetic mechanisms. It is now certain that interaction of genetic, epigenetic and environmental factors is responsible for the development of the disease.
Who reads Understanding the Genomic Background of Multifactorial Skin Diseases on the Example of Plaque Psoriasis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Nikoletta Nagy; University of Szeged Department of Dermatology and Allergology Albert Szent-Györgyi Medical Center; Zsuzsanna Bata-Csörgő; Lajos Kemény; Márta Széll
- Publisher
- Hungarian Dermatological Society
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)