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What is Dorsal Root Ganglion Neuron Excitability about?

1. Dorsal root ganglion (DRG) neurons express multiple sodium channel subtypes that influence their excitability. Small DRG neurons predominantly express TTX-resistant Nav1.8 and TTX-sensitive Nav1.7, while large DRG neurons predominantly express TTX-sensitive Nav1.1 and Nav1.6. 2. Nav1.8 contributes the upstroke of the action potential in small DRG neurons, while Nav1.7 may amplify subthreshold depolarizations. Nav1.1 and Nav1.6 contribute to the action potential in large DRG neurons. 3. Injury causes do

Author

Ricardo Alexis Niño Yevilao

Language

EN