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This study presents a continuous production process for influenza hemagglutinin-displaying virus-like particles (HA-VLPs) using an insect cell-baculovirus expression vector system (IC-BEVS) and a multi-stage bioreactor setup. The combination of a specific recombinant baculovirus and insect cell line resulted in efficient HA-VLP titers over a 20-day continuous operation, demonstrating the potential for integrated bioprocessing in vaccine production. The findings highlight the importance of optimizing residen

Author

Archell King

Language

EN