Can I read Resveratrol and Resveratrol Nano-delivery Systems in the Treatment of Inflammatory Bowel Disease on EtoBox?

Resveratrol and Resveratrol Nano-delivery Systems in the Treatment of Inflammatory Bowel Disease by Vemana Gowd; Kanika; Chandrashekhar Jori; Anis Ahmad Chaudhary; Hassan Ahmed Rudayni; Summya Rashid; Rehan Khan is a Medicine article available to read on EtoBox.

What is Resveratrol and Resveratrol Nano-delivery Systems in the Treatment of Inflammatory Bowel Disease about?

Inflammatory bowel disease (IBD) is a chronic disorder associated with the inflammation in the digestive tract. The exact cause of IBD is unknown; nevertheless, in IBD, the homeostasis of key regulatory factors involved in intestinal immunity has been documented to be disrupted. Despite the lack of a viable treatment for IBD, synthetic drugs and monoclonal antibodies are currently used to treat it. However, these treatments have side effects, and the high relapse rate limits their usage. Dietary polyphenols constitute a great variety of compounds and have shown an array of biological properties. Resveratrol is a natural polyphenol found in grapevines and berries. The therapeutic ability of resveratrol against IBD is amply demonstrated in many in vivo studies. Resveratrol can interact with several molecular targets (Nf-kB, SIRT1, mTOR, HIF-1α, miRNAs, and TNF-α) and effectively prevent/ alleviate IBD symptoms with promising results. Although resveratrol has profound anti-inflammatory properties against IBD, its therapeutic employment is limited due to its low water solubility, less chemical stability, less bioavailability, and rapid metabolism in vivo. Hence, resveratrol encapsulati

Who reads Resveratrol and Resveratrol Nano-delivery Systems in the Treatment of Inflammatory Bowel Disease?

Author

Vemana Gowd; Kanika; Chandrashekhar Jori; Anis Ahmad Chaudhary; Hassan Ahmed Rudayni; Summya Rashid; Rehan Khan

Publisher

Elsevier BV

Published

2022

Language

EN

Field

Medicine (Health Sciences)