Opening book details…
Can I read European-Australasian consensus on the management of advanced gastric and gastro-oesophageal junction cancer: current practice and new directions on EtoBox?
European-Australasian consensus on the management of advanced gastric and gastro-oesophageal junction cancer: current practice and new directions by Nick Pavlakis; Gary Tincknell; Lisi Elizabeth Lim; Kei Muro; Radka Obermannova; Sylvie Lorenzen; Yu Jo Chua; Chris Jackson; Christos Stelios Karapetis; Timothy Price; Lorraine Chantrill; Eva Segelov; Florian Lordick is a Medicine article available to read on EtoBox.
What is European-Australasian consensus on the management of advanced gastric and gastro-oesophageal junction cancer: current practice and new directions about?
Gastric carcinoma and gastro-oesophageal junction (GC/GEJ) carcinoma remain a significant global problem, with patients presenting with symptoms often found to have advanced or metastatic disease. Treatment options for these patients have broadened in recent years with new chemotherapy agents, agents targeting angiogenic pathways and the development of immune checkpoint inhibitors (ICIs). Most initial advances have occurred in the refractory setting, where it is important to balance treatment benefits __versus__ toxicity and patient quality of life. In the first-line treatment of advanced/metastatic GC/GEJ, platinum- and fluoropyrimidine-based chemotherapy protocols remain the backbone of therapy (with or without __HER2-__targeted therapy), with the FOLFIRI regimen offering an alternative in patients deemed unsuitable for a platinum agent. Microsatellite instability-high or mismatch repair-deficient cancers have been shown to benefit most from ICIs. In unselected patients previously treated with doublet or triplet platinum- and fluoropyrimidine-based chemotherapy and second-line chemotherapy with irinotecan or taxanes have formed the backbone of therapy with or without the addition
Who reads European-Australasian consensus on the management of advanced gastric and gastro-oesophageal junction cancer: current practice and new directions?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Nick Pavlakis; Gary Tincknell; Lisi Elizabeth Lim; Kei Muro; Radka Obermannova; Sylvie Lorenzen; Yu Jo Chua; Chris Jackson; Christos Stelios Karapetis; Timothy Price; Lorraine Chantrill; Eva Segelov; Florian Lordick
- Publisher
- SAGE Publications
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)