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Abnormal cortical and brain stem plasticity in Gilles de la Tourette syndrome: Abnormal M1 and Brain Stem Plasticity in GTS by Antonio Suppa; Daniele Belvisi; Matteo Bologna; Luca Marsili; Isabella Berardelli; Germana Moretti; Massimo Pasquini; Giovanni Fabbrini; Alfredo Berardelli is a Medicine article available to read on EtoBox.
What is Abnormal cortical and brain stem plasticity in Gilles de la Tourette syndrome: Abnormal M1 and Brain Stem Plasticity in GTS about?
We investigated primary motor cortex and brain stem plasticity in patients with Gilles de la Tourette syndrome. The study group comprised 12 patients with Gilles de la Tourette syndrome and 24 healthy subjects. Patients were clinically evaluated using the Yale Global Tic Severity Scale. We tested cortical plasticity by conditioning left primary motor cortex with intermittent or continuous theta-burst stimulation in 2 separate sessions. Test stimulation consisted of 20 motor-evoked potentials recorded from right first interosseous muscle before and after thetaburst stimulation. We also tested brain stem plasticity by conditioning the right supraorbital nerve with facilitatory electric high-frequency stimulation delivered at the same time as the late response of the blink reflex or inhibitory high-frequency stimulation delivered before the late response on 2 separate sessions. Test stimulation consisted of 10 blink reflexes from the right orbicularis oculi muscle before and after highfrequency stimulation. After intermittent theta-burst stimulation, motor-evoked potential amplitudes in healthy subjects increased significantly but remained unchanged in patients. Similarly, after conti
Who reads Abnormal cortical and brain stem plasticity in Gilles de la Tourette syndrome: Abnormal M1 and Brain Stem Plasticity in GTS?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Antonio Suppa; Daniele Belvisi; Matteo Bologna; Luca Marsili; Isabella Berardelli; Germana Moretti; Massimo Pasquini; Giovanni Fabbrini; Alfredo Berardelli
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0885-3185)
- Published
- 2011
- Language
- EN
- Field
- Medicine (Health Sciences)