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This document discusses epithelial mesenchymal transition (EMT) and its role in metastasis. EMT is a process where epithelial cells lose their adhesion and gain migratory properties. Key transcription factors that mediate EMT are the Snail family, including Snail, Slug, Zeb1 and Twist1. EMT occurs during normal developmental processes like neural tube formation but has also been shown to play a role in wound healing, inflammation, fibrosis and cancer metastasis. While much EMT research has been conducted in

Author

Bernard Wong Liang Yu

Language

EN