Can I read In vitro and In vivo inhibition of LPS-stimulated tumor necrosis factor-α secretion by the gallotannin β- d -pentagalloylglucose on EtoBox?
In vitro and In vivo inhibition of LPS-stimulated tumor necrosis factor-α secretion by the gallotannin β- d -pentagalloylglucose by Ken S. Feldman; Kiran Sahasrabudhe; Michael D. Lawlor; Sarah L. Wilson; Charles H. Lang; William J. Scheuchenzuber is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is In vitro and In vivo inhibition of LPS-stimulated tumor necrosis factor-α secretion by the gallotannin β- d -pentagalloylglucose about?
The naturally occurring gallotannin b-d-pentagalloylglucose (b-PGG) decreases tumor necrosis factor-alpha (TNF-a) output from human peripheral blood mononucleocytes exposed to lipopolysaccharide (LPS) by as much as 90% (vs control) at $5 mM concentration. A qualitatively similar but less pronounced effect ($ 50% decrease) was observed in the serum of rats dosed with both LPS and b-PGG. These results may have relevance to therapies that target disease states characterized by an overproduction of TNF-a.
Who reads In vitro and In vivo inhibition of LPS-stimulated tumor necrosis factor-α secretion by the gallotannin β- d -pentagalloylglucose?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Ken S. Feldman; Kiran Sahasrabudhe; Michael D. Lawlor; Sarah L. Wilson; Charles H. Lang; William J. Scheuchenzuber
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0960-894X)
- Published
- 2001
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)