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Kinetics of Meiotic Maturation in Oocytes from Unstimulated Ovaries and Duration of Pronucleus Presence and Preimplantation Development by SHIRASAWA, Hiromitsu; KUMAZAWA, Yukiyo; TAKAHASHI, Kazumasa; GOTO, Mayumi; SATO, Wataru; ONO, Natsuki; TOGASHI, Kazue; MAKINO, Kenichi; WAGA, Masato; SATO, Naoki; TERADA, Yukihiro is a Medicine article available to read on EtoBox.
What is Kinetics of Meiotic Maturation in Oocytes from Unstimulated Ovaries and Duration of Pronucleus Presence and Preimplantation Development about?
## Objective: To evaluate the meaning of meiotic maturation kinetics and duration of pronucleus presence (dpp) for parthenogenetic activation outcome. ## Design: Retrospective study. ## Setting: University hospital. ## Patient(s): Eight patients with endometrioid adenocarcinoma and 65 patients who underwent in vitro fertilization (ivf) with intracytoplasmic sperm injection (icsi). ## Intervention(s): After collection of oocytes from nonstimulated ovaries of patients with endometrioid adenocarcinoma, in vitro maturation (ivm) and parthenogenetic activation performed with time-lapse imaging; after icsi, embryos similarly incubated with time-lapse imaging. ## Main outcome measure(s): Timing of the release of the first polar body (fpb), dpp, and developmental stage with ivm and parthenogenetic activation; after icsi, assessment of dpp and preimplantation developmental stage. ## Result(s): With ivm, 55.2% of oocytes matured; 53.1% of fpbs were released within 24 hours, and 46.9% of fpbs were released after 24 hours. regarding developmental stage, oocytes that released fpb later during ivm tended to develop more than oocytes that released the fpb within 24 hours. for embryos from parthen
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- Author
- SHIRASAWA, Hiromitsu; KUMAZAWA, Yukiyo; TAKAHASHI, Kazumasa; GOTO, Mayumi; SATO, Wataru; ONO, Natsuki; TOGASHI, Kazue; MAKINO, Kenichi; WAGA, Masato; SATO, Naoki; TERADA, Yukihiro
- Publisher
- Elsevier Inc. (ISSN 2666-335X)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)