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Can I read Approach to the Patient: Insulinoma on EtoBox?
Approach to the Patient: Insulinoma by Johannes Hofland; Julie C Refardt; Richard A Feelders; Emanuel Christ; Wouter W de Herder is a Medicine article available to read on EtoBox.
What is Approach to the Patient: Insulinoma about?
## Abstract Insulinomas are hormone-producing pancreatic neuroendocrine neoplasms with an estimated incidence of 1 to 4 cases per million per year. Extrapancreatic insulinomas are extremely rare. Most insulinomas present with the Whipple triad: (1) symptoms, signs, or both consistent with hypoglycemia; (2) a low plasma glucose measured at the time of the symptoms and signs; and (3) relief of symptoms and signs when the glucose is raised to normal. Nonmetastatic insulinomas are nowadays referred to as “indolent” and metastatic insulinomas as “aggressive.” The 5-year survival of patients with an indolent insulinoma has been reported to be 94% to 100%; for patients with an aggressive insulinoma, this amounts to 24% to 67%. Five percent to 10% of insulinomas are associated with the multiple endocrine neoplasia type 1 syndrome. Localization of the insulinoma and exclusion or confirmation of metastatic disease by computed tomography is followed by endoscopic ultrasound or magnetic resonance imaging for indolent, localized insulinomas. Glucagon-like peptide 1 receptor positron emission tomography/computed tomography or positron emission tomography/magnetic resonance imaging is a highly se
Who reads Approach to the Patient: Insulinoma?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Johannes Hofland; Julie C Refardt; Richard A Feelders; Emanuel Christ; Wouter W de Herder
- Publisher
- Oxford University Press
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)