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Low Antroduodenal Pressure Gradients Are Responsible for Gastric Emptying of a Low‐caloric Liquid Meal in Humans by T. HAUSKEN; M. MUNDT; M. SAMSOM is a Medicine article available to read on EtoBox.

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The motor mechanisms responsible for transpyloric flow of gastric contents are still poorly understood. The aim of our study was to investigate the relationship between luminal pressures and gastric wall motion and between gastroduodenal pressure gradients and pressure waves, and ante‐ and retro‐grade transpyloric flow. In eight healthy volunteers, intraluminal pressures were recorded from the antrum and proximal duodenum. Transpyloric flow was monitored simultaneously using duplex ultrasonography, before, during and after ingestion of 300 mL meat soup. Transpyloric emptying occurred as sequences of alternating periods of emptying–reflux–emptying. Approximately one‐third of the sequences were not associated with peristalsis. The antroduodenal pressure gradients were significantly lower during nonperistaltic‐related emptying than during peristaltic‐related emptying (0.15 (0–0.3) kPa, and 1.7 (0.2–2.0) kPa, respectively [mean ± (range)], P < 0.005). The duration of emptying episodes not associated with peristalsis were significantly longer than those associated with peristalsis at (6.5 (3–8.7) s and 4.4 (2–6) s, respectively, P=0.059). Manometry detected only 56% of the antral contra

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Author

T. HAUSKEN; M. MUNDT; M. SAMSOM

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 1350-1925)

Published

2002

Language

EN

Field

Medicine (Health Sciences)