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Prognosis and Prognostic Factors in Node-negative Cervix Cancer by M. Stockler; P. Russell; S. McGahan; P.M. Elliott; C. Dalrymple; M. Tattersall is a Medicine article available to read on EtoBox.

What is Prognosis and Prognostic Factors in Node-negative Cervix Cancer about?

Relapse rates, mortality rates and possible prognostic factors were assessed in women with early-stage, node-negative cervix cancer. We identified 194 women who had a radical hysterectomy with histopathologically confirmed negative lymph nodes as primary ~eatment for FIGO stages IB and IIA cervix cancer between 1981 and1990, at a single tertiary referral oncology centre. Each patient's pathology was reviewed by two pathologists blinded to patient outcome. Clinical and demographic details were abstracted from medical records by a single observer blinded to patient outcome. Median follow-up was 5.3 years and 95% were followed for longer than 2 years. Prognostic significance for relapse-free survival was assessed with Cox's proportional hazards model. There were 27 relapses (relapse-free survival probability of 85% (95% confidence interval (CI): 79-90)) and 19 deaths (overall survival probability 86% (95%CI: 78--93)), of which 17 were due to cervix cancer (cervix cancer specific survival probability 87% (95%CI: 80--94)). Nuclear grade 2 or 3 (P = 0.02) and small-cell squamous histology (P = 0.01) were each associated with about a four-fold increase in the risk of recurrence, while lym

Who reads Prognosis and Prognostic Factors in Node-negative Cervix Cancer?

Author

M. Stockler; P. Russell; S. McGahan; P.M. Elliott; C. Dalrymple; M. Tattersall

Publisher

John Wiley and Sons; BMJ; Wolters Kluwer Health; Ovid Technologies (Wolters Kluwer Health) (ISSN 1048-891X)

Published

1996

Language

EN

Field

Medicine (Health Sciences)