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Can I read Preparation of Stereo‐Divergent Compounds from the Natural Product Drupacine Based on Complexity‐to‐Diversity Strategy on EtoBox?

Preparation of Stereo‐Divergent Compounds from the Natural Product Drupacine Based on Complexity‐to‐Diversity Strategy by Yalin Li; Yuxing Cai; Xingyu Pan; Junyi Dong; Yuhang Tan; Huiling Zeng; Zhanpeng Yu; Chen Chen; Lingyi Kong; Jianguang Luo is a Agricultural and Biological Sciences article available to read on EtoBox.

What is Preparation of Stereo‐Divergent Compounds from the Natural Product Drupacine Based on Complexity‐to‐Diversity Strategy about?

The Complexity-to-Diversity (CtD) strategy was applied to synthesize a 23-member compound collection from the natural product drupacine, including 21 novel compounds. An unusual benzo[d]cyclopent[b]azepin skeleton was constructed by Von Braun reaction to cleave C-N bond of drupacine. Moreover, compound 10 has potential cytotoxicity to human colon cancer cells with low toxicity to the normal human colon mucosal epithelial cell lines.

Who reads Preparation of Stereo‐Divergent Compounds from the Natural Product Drupacine Based on Complexity‐to‐Diversity Strategy?

It is typically read by researchers, students, and practitioners in Agricultural and Biological Sciences.

Author
Yalin Li; Yuxing Cai; Xingyu Pan; Junyi Dong; Yuhang Tan; Huiling Zeng; Zhanpeng Yu; Chen Chen; Lingyi Kong; Jianguang Luo
Publisher
Wiley
Published
2023
Language
EN
Field
Agricultural and Biological Sciences (Life Sciences)