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A Closed Unventilated Chamber for the Measurement of Transepidermal Water Loss by Jouni Nuutinen; Esko Alanen; Pekka Autio; Marjo‐Riitta Lahtinen; Ilkka Harvima; Tapani Lahtinen is a Medicine article available to read on EtoBox.

What is A Closed Unventilated Chamber for the Measurement of Transepidermal Water Loss about?

**Background/aims** Open chamber systems for measuring transepidermal water loss (TEWL) have limitations related to ambient and body‐induced airflows near the probe, probe size, measurement sites and angles, and measurement range. The aim of the present investigation was to develop a closed chamber system for the TEWL measurement without significant blocking of normal evaporation through the skin. Additionally, in order to use the evaporimeter to measure evaporation rates through other biological and non‐biological specimens and in the field applications, a small portable, battery‐operated device was a design criteria. **Methods** A closed unventilated chamber (inner volume 2.0 cm^3^) was constructed. For the skin measurement, the chamber with one side open (open surface area 1.0 cm^2^) is placed on the skin. The skin application time was investigated at low and high evaporation rates in order to assess the blocking effect of the chamber on normal evaporation. From the rising linear part of the relative humidity (RH) in the chamber the slope was registered. The slope was calibrated into a TEWL value by evaporating water at different temperatures and measuring the water loss of heat

Who reads A Closed Unventilated Chamber for the Measurement of Transepidermal Water Loss?

Author

Jouni Nuutinen; Esko Alanen; Pekka Autio; Marjo‐Riitta Lahtinen; Ilkka Harvima; Tapani Lahtinen

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0909-752X)

Published

2003

Language

EN

Field

Medicine (Health Sciences)