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Immediate Versus Staged Multivessel PCI Strategies in Patients with ST-Segment Elevation Myocardial Infarction and Multivessel Disease: A Systematic Review and Meta-Analysis by Hu, Meng-Jin (author);Yang, Yue-Jin (author);Yang, Jin-Gang (author) is a nonfiction available to read on EtoBox.

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## Background: Recent guidelines and randomized clinical trials favor the multivessel percutaneous coronary intervention (mv-pci) strategy undertaken immediately or staged after primary pci in patients with st-segment elevation myocardial infarction (stemi) and multivessel disease. however, the optimal strategy of mv-pci remains unknown. ## Methods: We conducted a search of pubmed, embase, web of science, the cochrane database (central), clinicaltrial.gov, and google scholar for studies comparing immediate versus staged mv-pci in patients with stemi and multivessel disease. pooled odds ratios (or) and 95% confidence intervals (ci) were estimated using random-effects models. ## Results: Eighteen (4 randomized clinical trials) studies with 8100 patients fulfilled the inclusion criteria. relative to staged mv-pci, immediate mv-pci was associated with higher short-term (within 30 days) (or, 3.96; 95% ci, 2.07-7.59; p < 0.0001) and long-term (above 6 months) mortality (or, 2.12; 95% ci, 1.46-3.07; p < 0.0001), short-term major adverse cardiovascular events (mace)(or, 1.99; 95% ci, 1.13-3.50; p = 0.02) and cardiac death (or, 4.78; 95% ci, 2.17-10.53; p = 0.0001). there was a nonsignifica

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Author

Hu, Meng-Jin (author);Yang, Yue-Jin (author);Yang, Jin-Gang (author)

Publisher

Elsevier BV

Published

2021

Language

EN

Category

nonfiction