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What is Understanding Pulmonary Arterial Hypertension about?

This review discusses pulmonary arterial hypertension (PAH), characterized by a resting mean pulmonary artery pressure of 25 mm Hg or above, and its pathogenesis, clinical management, and treatment options. The document highlights the complex mechanisms involved in PAH, including vascular remodeling, abnormal cell proliferation, and the role of genetic and epigenetic factors, while noting that current therapies primarily improve symptoms without reducing mortality. It also summarizes the epidemiology and cl

Author

Fernando Cisneros

Language

EN