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Evaluation of the Role of Ghrelin and Leptin as Biochemical Markers in Female with Polycystic Ovarian Syndrome by Mahmod Khalil Ibrahim; Amina Hamed Ahmed Alobaidi is a Medicine article available to read on EtoBox.

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## Introduction: Polycystic ovary syndrome (pcos) is the most common endocrine disorder in women of reproductive age. pcos is a heterogeneous complex disorder of defined aetiology. some studies report its association with various endocrine, metabolic and immunological abnormalities. the hunger hormones ghrelin and leptin affect the pathogenesis of pcos and might lead to the development of metabolic syndrome (ms) in obese women. ## Aim: The study aims at evaluating the role of ghrelin and leptin level in females with polycystic ovary syndrome as a biochemical marker for the diagnosis and monitoring progression. ## Subjects and methods: The study included one hundred pcos patients and fifty apparently healthy subjects with regular menstrual cycle, visiting gynecology outpatient clinic of kalar general hospital, from the beginning of february 2015 to the end of june 2015. body mass index (bmi) along with serum ghrelin, leptin, luteinizing hormone (lh), follicle stimulating hormone (fsh) and testosterone levels were measured for both groups. serum leptin was determined using sandwich elisa, while serum ghrelin was determined using competitive elisa. differences between patient and cont

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Author

Mahmod Khalil Ibrahim; Amina Hamed Ahmed Alobaidi

Published

2021

Language

EN

Field

Medicine (Health Sciences)