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Acceptor Substrate Specificity of UDP-Gal GlcNAc-R by yashirunakamura is a document available to read on EtoBox.
The study investigates the acceptor substrate specificity of the UDP-Gal: GlcNAc-R β1,3-galactosyltransferase (WbbD) from Escherichia coli O7:K1, revealing that WbbD has distinct substrate preferences compared to mammalian β4-galactosyltransferase I. WbbD efficiently transfers Gal to specific lipid-linked GlcNAc substrates, and its activity is influenced by the presence of pyrophosphate and lipid moieties. The findings contribute to understanding O antigen synthesis and the potential development of specific
- Author
- yashirunakamura
- Language
- EN