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What is Genetic Polymorphisms and Weight Gain in Schizophrenia about?

The study examines the impact of genetic polymorphisms in the 5-HT2C receptor and MDR1 on weight gain in female schizophrenic patients treated with second generation antipsychotics olanzapine and risperidone. Results indicate that the 5-HT2C polymorphism does not significantly influence weight gain, while MDR1 variants may affect risperidone-induced weight gain due to their association with increased drug accessibility to the brain. The findings suggest a potential genetic basis for weight gain in patients

Author

Cristian Vargas

Language

EN