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This study investigates the effects of polyaminergic agents, specifically spermidine (SPD) and arcaine, on the reconsolidation of conditioned fear in male Wistar rats. Results indicate that SPD enhances memory reconsolidation at certain doses, while arcaine impairs it, suggesting that modulation of the polyamine-binding site on NMDA receptors plays a significant role in memory processes. The findings highlight the potential for pharmacological interventions to influence memory reconsolidation through these
- Author
- estelacostapsi
- Language
- EN