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What is Acyl Carrier Proteins in Polyketide Biosynthesis about?
This review explores the role of acyl carrier proteins (ACPs) in type II polyketide biosynthesis, highlighting their importance in shuttling building blocks and intermediates for the synthesis of complex, pharmacologically relevant molecules. The authors discuss the structural dynamics and interactions of ACPs, emphasizing the need for a deeper understanding of their function to facilitate the engineering of polyketide synthases for novel drug development. Advances in chemical probing and molecular dynamics
- Author
- Hieu Tran
- Language
- EN