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Synthesis And Biological Activity Of 3-aryl-1-(3-methyl-5- Styryl-4-isoxazolyl)-2-oxo-(1h,3h,5h)-pyrimidine-4,6-diones by E. Rajanarendar; K. Thirupathaiah; E. Kalyan Rao; A. Siva Rami Reddy is a Chemistry article available to read on EtoBox.

What is Synthesis And Biological Activity Of 3-aryl-1-(3-methyl-5- Styryl-4-isoxazolyl)-2-oxo-(1h,3h,5h)-pyrimidine-4,6-diones about?

A Series of 3-aryl-1 -(3-methyl-5-styryl-4-isoxazolyl)-2-oxo-(l //, 3//, 5H)pyrimidine-4,6 diones 3 have been prepared from l-aryl-3-(-3-methyl-5-styryl-4isoxazolyl)ureas 2 by heating with malonic acid in acetyl chloride. Compounds 2 are obtained by interaction of 4-amino-3-methyl-5 styrylisoxazole 1 with aryl isocyanates. The analytical and spectral data agree well with the structuresof 2 and 3. Antibacterial and antifungal activity of compounds 2 and 3 have been studied. Vol. 14, No. 5, 2008 Synthesis and Biological Activity of 3-Aryl-l-(3-Methyl-5-Styryl-4-lsoxazolyl)-2-Oxo-

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Author

E. Rajanarendar; K. Thirupathaiah; E. Kalyan Rao; A. Siva Rami Reddy

Publisher

Walter de Gruyter GmbH

Published

2008

Language

EN

Field

Chemistry (Physical Sciences)