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Quantification of Masticatory Muscle Atrophy After High-dose Radiotherapy by Alan M Nichol; Sally L Smith; Yulia D’yachkova; James L Robar; Leigh R Barrett; Jennifer L Rolleston; John H Hay is a Medicine article available to read on EtoBox.

What is Quantification of Masticatory Muscle Atrophy After High-dose Radiotherapy about?

## Purpose: To determine the rate of change in the cross-sectional area of the masticatory muscles after radiotherapy. ## Methods and materials: Eligible patients had undergone unilateral radiotherapy between 1993 and 2000 and had a baseline ct scan, a comparable follow-up ct scan a minimum of 1 year later, and no recurrence of cancer. fourteen patients had their ct series scanned into digital image files. two anatomically selected ct slices were bisected by the midline sagittal plane and stored under randomly assigned file names. three observers measured the masseter and medial pterygoid areas on two occasions. ## Results: The intraobserver reliability of the muscle area measurements was 96.3% for the masseter and 97.1% for the medial pterygoid. the interobserver reliability of the muscle area measurements was 96.7% for the masseter and 96.3% for the medial pterygoid. on the treated side, the muscles received a median dose of 56 gy (range 47-63) in 2.0-0.4-gy fractions. with a median follow-up of 2.9 years (range 1-7.6), mixed-effects regression analysis demonstrated a significant area of reduction of -0.17 cm(2)/y (p = 0.0001) for the masseter and -0.13 cm(2)/y (p = 0.001) for th

Who reads Quantification of Masticatory Muscle Atrophy After High-dose Radiotherapy?

Author

Alan M Nichol; Sally L Smith; Yulia D’yachkova; James L Robar; Leigh R Barrett; Jennifer L Rolleston; John H Hay

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)

Published

2003

Language

EN

Field

Medicine (Health Sciences)