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What is Cranberry Proanthocyanidins Inhibit P. aeruginosa about?

Cranberry-derived proanthocyanidins (cerPAC) were shown to impair virulence and inhibit quorum sensing in the pathogenic bacterium Pseudomonas aeruginosa. In laboratory experiments, cerPAC reduced production of virulence factors like proteases and protected fruit flies from fatal P. aeruginosa infection. Analysis found cerPAC reduced quorum sensing signal molecules and inhibited genes involved in quorum sensing. Molecular modeling suggested cerPAC binds to quorum sensing transcriptional regulators. The stud

Author

Anonymous 6OPLC9U

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EN