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Can I read Encapsulation and controlled release of vitamin C in modified cellulose nanocrystal/chitosan nanocapsules on EtoBox?
Encapsulation and controlled release of vitamin C in modified cellulose nanocrystal/chitosan nanocapsules by Jiyoo Baek; Mohankandhasamy Ramasamy; Natasha Carly Willis; Dae Sung Kim; William A. Anderson; Kam C. Tam is a Agricultural and Biological Sciences article available to read on EtoBox.
What is Encapsulation and controlled release of vitamin C in modified cellulose nanocrystal/chitosan nanocapsules about?
Vitamin C (VC), widely used in food, pharmaceutical and cosmetic products, is susceptible to degradation, and new formulations are necessary to maintain its stability. To address this challenge, VC encapsulation was achieved via electrostatic interaction with glycidyltrimethylammonium chloride (GTMAC)-chitosan (GCh) followed by cross-linking with phosphorylated-cellulose nanocrystals (PCNC) to form VC-GCh-PCNC nanocapsules. The particle size, surface charge, degradation, encapsulation efficiency, cumulative release, free-radical scavenging assay, and antibacterial test were quantified. Additionally, a simulated human gastrointestinal environment was used to assess the efficacy of the encapsulated VC under physiological conditions. Both VC loaded, GCh-PCNC, and GCh-Sodium tripolyphosphate (TPP) nanocapsules were spherical with a diameter of 450 ± 8 and 428 ± 6 nm respectively. VC-GCh-PCNC displayed a higher encapsulation efficiency of 90.3 ± 0.42% and a sustained release over 14 days. The release profiles were fitted to the first-order and Higuchi kinetic models with R^2^ values greater than 0.95. VC-GCh-PCNC possessed broad-spectrum antibacterial activity with a minimum inhi
Who reads Encapsulation and controlled release of vitamin C in modified cellulose nanocrystal/chitosan nanocapsules?
It is typically read by researchers, students, and practitioners in Agricultural and Biological Sciences.
- Author
- Jiyoo Baek; Mohankandhasamy Ramasamy; Natasha Carly Willis; Dae Sung Kim; William A. Anderson; Kam C. Tam
- Publisher
- Elsevier
- Published
- 2021
- Language
- EN
- Field
- Agricultural and Biological Sciences (Life Sciences)