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Effect of Ethanol on Ultrafiltration of Bovine Albumin Solutions with Organic Membranes by M.Y. Jaffrin; L.H. Ding; Ch. Couvreur; P. Khari is a Engineering article available to read on EtoBox.

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This paper investigates the ultrafiltration of albumin-ethanol solutions on polysulfone hollow fiber membranes with 30 kDa cut-off. The aim is to identify the mechanisms responsible for the observed permeate flux reduction in presence of ethanol. The variations of permeate flux with transmembrane pressure and wall shear rate fit the usual pattern of flux limitation by concentration polarization. Thus, although ethanol significantly increases the permeate viscosity, the data show that the flux decrease is not a direct consequence of the viscosity increase but rather due to reduced albumin diffusivity which decreases the back transport to the bulk solution. The specific resistance of the albumin layer on the membrane was found to be unaffected by the presence of ethanol. However the fouling potential of our solutions was found to be significantly increased by the addition of ethanol. Thus the observed flux reduction due to ethanol seems to be explained by a combination of a thicker polarization layer caused by reduced back transport and increased membrane fouling. A 10% increase in filtrated volume can be obtained by imposing periodic retrofiltrations which decrease fouling.

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Author

M.Y. Jaffrin; L.H. Ding; Ch. Couvreur; P. Khari

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0376-7388)

Published

1997

Language

EN

Field

Engineering (Physical Sciences)