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This document discusses the impact of cellular aging on neurons, emphasizing the limited capacity for renewal and the relationship between advanced neuronal age and neurodegenerative diseases. It highlights recent findings on how aging affects nuclear structures and the epigenetic landscape, which are crucial for understanding age-related brain dysfunction. The review underscores the importance of molecular mechanisms in neuronal aging to inform potential therapeutic interventions for cognitive decline and

Author

Amanda Azevedo

Language

EN