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Comparison of Natural Histories of Human Papillomavirus Detected by Clinician- and Self-sampling by Anna-Barbara Moscicki; Lea Widdice; Yifei Ma; Sepideh Farhat; Susanna Miller-Benningfield; Janet Jonte; Julie Jay; Cheryl Godwin de Medina; Evelyn Hanson; Lisa Clayton; Stephen Shiboski is a Medicine article available to read on EtoBox.
What is Comparison of Natural Histories of Human Papillomavirus Detected by Clinician- and Self-sampling about?
## Abstract New strategies for cervical cancer screening include human papillomavirus (HPV) DNA testing. Using self‐testing methods would increase access to testing in both developed and developing countries. The purpose of this study was to compare time‐to‐clearance of specific HPV types between clinician‐collected‐lavage (CC‐L) and self‐collected (SC) sampling in a single cohort. CC‐L and SC samples were obtained every 4 months at alternate 2‐month windows from 537 women. Eighteen high‐risk (HR) HPV and 4 low‐risk (LR) HPV were examined. Proportional hazards model was used to compare time‐to‐clearance between methods for combined HR and for 13 specific HPV types. Prentice‐Wilcoxon test was used for within‐subject paired comparison. In the independent analysis for combined HR and LR types, no differences were found. For specific types, time‐to‐clearance for all HPV types examined between CC‐L and SC samples was similar except for HPV 66 which showed a trend to clear slower by SC (__p__ = 0.09). When comparing methods in the same woman, time‐to‐clearance was similar for all types except for HPV 16 which showed a trend to clear slower by CC‐L means (__p__ = 0.08). When we examined p
Who reads Comparison of Natural Histories of Human Papillomavirus Detected by Clinician- and Self-sampling?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Anna-Barbara Moscicki; Lea Widdice; Yifei Ma; Sepideh Farhat; Susanna Miller-Benningfield; Janet Jonte; Julie Jay; Cheryl Godwin de Medina; Evelyn Hanson; Lisa Clayton; Stephen Shiboski
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square; Test accounts (ISSN 0020-7136)
- Published
- 2010
- Language
- EN
- Field
- Medicine (Health Sciences)